High-throughput phenotypic screening using stem cell-derived oligodendrocytes

Drug Discovery in Regenerative Medicine – a Case Study

Learn how Dr. Paul Tesar and colleagues, at the Case Western Reserve University School of Medicine in Cleveland, rapidly identified promising molecules for multiple sclerosis therapy.

Summary
In this case study, learn how:
  • The phenotypic screening assay was set up on the Operetta® high-content analysis system.
  • Complex phenotypic changes, such as differentiation of oligodendrocytes, can be reliably quantified.
  • High-content screening, combined with cutting-edge stem cell technology, plays a key role in drug discovery within regenerative medicine

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